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When the vitreous gel is removed surgically, it is replaced by fluid, which does not provide a comparable level of inhibition of diffusion

Sweeney, G., et al., The antihyperglycemic drug alpha-lipoic acid stimulates glucose uptake via both GLUT4 translocation and GLUT4 activation: potential role of p38 mitogen-activated protein kinase in GLUT4 activation

In men, significant weight loss from these agents may improve obesity-related hypogonadism, testosterone levels, and cardiovascular risk factors

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4.5.3.3 Current validation framework status Although numerous studies employ area under receiver operating characteristic curves exceeding 0.8 as diagnostic performance criteria, validation data from independent external cohorts remain insufficient